The region in which Northlands College is located encompasses 46 per cent of Saskatchewan’s land mass but has less than four per cent of its population. The college has campuses in Air Ronge, La Ronge, Buffalo Narrows and Creighton, and offers select programs in other communities in northern Saskatchewan. Program areas include health, trades, adult basic education, mining and university courses. Students can complete a four-year bachelor of science in nursing at Northlands in partnership with the University of Saskatchewan.

In 2017, Northlands opened a mine school, offering both diploma and certificate training. Its mine-engineering technician diploma is the only one in Canada offering in-class instruction along with labs, field schools and a work placement. Students work in a simulator to hone their skills with relevant equipment before they enter the field. The school also offers a civil technician certificate, and recently introduced a mineral exploration techniques program. This one-year certificate program explores geology and geomorphology through labs and field work.

The La Ronge campus has student apartments and there are small residences in Creighton and Buffalo Narrows. Northlands College is one of seven regional colleges that provide courses created by other educational providers.